Buy Augmentin online

Catalog Antibiotics

Availability: In Stock (29 packs)

Active Ingredient: Clavulanate, Amoxicillin

Manufacturer: Alkem Laboratories Ltd (Cytomed) / GlaxoSmithKline Plc

Disease(s): Infections of lower respiratory tract / otitis media / sinusitis / skin infections / urinary tract infections.

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Augmentin Reviews

Augmentin is used in the treatment of lower respiratory, middle ear, sinus, skin, and urinary tract infections that are caused by certain specific bacteria. These bacteria produce a chemical enzyme called beta lactamase that makes some infections particularly difficult to treat.

375MG
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625MG
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30 pills $2.38 $71.36 ADD TO CART
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120 pills $1.54 $101.16 $285.46 $184.30 ADD TO CART
180 pills $1.44 $168.60 $428.19 $259.59 ADD TO CART
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1000MG
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180 pills $2.58 $324.76 $788.40 $463.64 ADD TO CART
270 pills $2.54 $496.69 $1182.60 $685.91 ADD TO CART

What is Augmentin?

Augmentin is a broad-spectrum antibiotic that contains amoxicillin and clavulanic acid. It is active against a large number of gram-positive and gram-negative microorganisms and has a bactericidal effect.

Pharmacological action of Augmentin

Augmentin, due to its clavulanic acid, suppresses the activity of beta-lactamases, enzymes producing microorganisms that are usually resident to penicillins and cephalosporins. This helps to expand the spectrum of antibacterial effects of the drug. When using Augmentin, the plasma concentration of amoxicillin is the same as that formed by oral administration of equivalent doses of amoxicillin alone. Both components of Augmentin are characterized by rapid absorption from the digestive tract, their therapeutic concentration is found in tissues and organs, as well as in liquid media. Experimental studies conducted on animals have shown Augmentin’s ability to penetrate the placental barrier, but no data have been obtained confirming its negative effect on the fetus. Amoxicillin is excreted mainly by renal excretion and partly with urine, clavulanic acid — both through the kidneys and extrarenal mechanisms. After taking Augmentin for 6 hours, approximately 60–70% of amoxicillin and 40–60% of clavulanic acid are excreted in the urine unchanged.

Indications for the use of Ampicillin

According to the instructions Augmentin is used for bacterial infections caused by microorganisms sensitive to the drug. These include:

  • Infections of the respiratory tract — pneumonia, inflammation of the bronchi, empyema, bronchopneumonia, lung abscesses;
  • Infections of the skin and soft tissues — burns, wound infections, abscesses;
  • Infections of the genitourinary system — pyelonephritis, cystitis, urethritis, pelvic infections, gonorrhea, syphilis;
  • Osteomyelitis;
  • Peritonitis.

Also, the use of Augmentin is indicated for infectious complications in the postoperative period.

Methods of use and dosage

In accordance with the instructions, Augmentin is recommended to be taken at the beginning of a meal, doses of the drug are prescribed individually depending on the age of the patient and the severity of the infection. With treatment, it is possible to carry out step therapy — first, intravenous administration of the drug is used, and then they switch to oral administration. The course of treatment with Augmentin usually does not exceed 14 days without revising the clinical picture. For adults and children over 12 years of age, it is prescribed for mild and moderate infections 1 tablet 0.375 g 3 times a day, for severe illness 1 tablet 0.625 g or 2 tablets 0.375 g 3 times a day. With intravenous administration, it is allowed to use the drug every 6 hours with a maximum daily dose of 7.2 g. Patients with impaired renal function during treatment require correction of the prescribed doses of the drug.

Augmentin for children under 1 year of age is usually prescribed in the form of drops. The instructions indicate that at the age of up to 3 months, a single dosage is 0.75 ml, from 3 to 12 months — 1.25 ml. In case of severe infection with intravenous administration of the drug every 6-8 hours, a single dose of Augmentin for children from 3 months to 12 years old is 30 mg / kg body weight, up to 3 months at the same dose every 12 hours. Also, children under 12 years of age are prescribed a suspension of Augmentin or syrup. According to the instructions, children from 9 months to 2 years are prescribed 2.5 ml (0.156 g / 5 ml), from 2 to 7 years — 5 ml (0.156 g / 5 ml), from 7 to 12 years — 10 ml (0.156 g / 5 ml) three times a day, with severe illness, the dose is allowed to double.

Augmentin suspension is prepared for use immediately before use, the powder is dissolved in boiled water at room temperature. Water is added to the mark marked on the vial, while the contents are gradually gently shaken, and then settled until completely dissolved in about 5 minutes. Before each use, the vial must be shaken vigorously, to determine the exact dosage, a measuring cap-cap is used, carefully rinsed with water after each use. The diluted suspension is stored in the refrigerator for no more than 7 days, but does not freeze.

Contraindications:

According to the instructions, Augmentin is not recommended for use in cases of severe previous hypersensitivity reaction to penicillins, cephalosporins or other allergens, with suspected infectious mononucleosis, during pregnancy, as well as women who are breast-feeding. With special caution, the use of the drug is prescribed for serious impaired liver function and, if the patient has a history of various allergic reactions. With signs of an erythematous rash or urticaria, it is recommended to stop treatment, it is also not advisable to take Augmentin simultaneously with Probenecid and Allopurinol.

Side effects:

The use of Augmentin may cause the following side effects:
  • Digestive disorder (you can reduce the severity by taking the drug with food);
  • Dysfunction of the liver, the development of hepatitis, cholestatic jaundice;
  • Urticaria, allergic edema, extremely anaphylactic shock;
  • Polyform erythema, Stevens-Johnson syndrome;
  • Exfoliative dermatitis;
  • Dizziness, headache;
  • Candidiasis.
There is information about isolated cases of the development of pseudomembranous colitis, it is also occasionally possible at the injection site to develop inflammation of the vein (phlebitis).